Gabapentin and Cognitive Decline: A Hidden Risk

Angie Szumlinski
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October 7, 2025
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Ever stop to wonder what’s actually being prescribed to caregivers when they walk into the occupational health clinic with back pain? The connection between gabapentin and cognitive decline might not be widely known—but it’s becoming too important to ignore. Many providers reach for gabapentin as a go-to option for chronic low back pain, especially in younger adults, viewing it as a safer alternative to opioids. But fresh research is beginning to challenge that idea.

A study published in BMJ Journal of Regional Anesthesia and Pain Medicine found a troubling link: gabapentin prescribed for adults with chronic low back pain may significantly increase the risk of dementia and cognitive impairment—particularly in non-elderly adults. That’s a startling insight when you think about how many of your direct care staff deal with back pain on a regular basis. The physical demands of caregiving take a toll, and aches and strains are among the most common complaints seen at occupational health visits.

So what are providers recommending in those situations? If gabapentin is on the table, it’s time to dig deeper. While we always want to respect clinical expertise, a little staff education could go a long way in helping caregivers become more informed and empowered health consumers. According to this PubMed article summarizing the study and the original research in the BMJ Journal of Regional Anesthesia and Pain Medicine, the potential connection between gabapentin and cognitive decline warrants caution—especially when the drug is used long-term.

A quick meeting with your occupational health provider might be all it takes to make sure they’re familiar with this research and using the medication judiciously. Taking that extra step shows that your community is thinking ahead and advocating for those who work so hard within it.

Stay well and stay informed!


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